No interactions were found between E.E.S.-400 and Glucophage. Studies have found that Antabuse can be successful in reducing the number of drinking days and increasing the number of days of abstinence, particularly in combination with counseling and support. However, it is important to note that Antabuse is not a standalone solution, and successful treatment typically involves a combination of medication, therapy, and lifestyle changes. In April 2023, French pharmaceutical company Sanofi, which supplies Antabuse in the UK and worldwide, decided to stop producing Antabuse due to a combination of low supply issues and poor profit margins for the medication.
Antabuse was prescribed to people with alcohol problems in the UK in significant numbers until 2016. UK doctors had found several issues with Disulfiram.
